Endemik İnsan Koronavirüsü’ (Covid-19) nün, Moleküler Biyolojisi, Replikasyonu, Patogenezi, Kaynakları ve Tarihine Genel Bakış



Coronaviruses (CoVs) are enveloped, positive strand RNA viruses in the Coronoviridae family. It first appeared in the 1930s when it caused acute respiratory infections in chickens. In the 1940s, it was characterized, as mouse hepatitis virus (MHV) and infectious gastroenteritis virus (TGEV). Human coronaviruses walk out in the 1960s with the appearance of upper respiratory tract infections in children. These viruses are not deadly and demonstrate symptoms like colds and flu. Nevertheless these viruses subsequently mutated and became fatal. The 2019 new type of coronavirus (COVID-19) was first stated in Wuhan, the capital of China’s Hubei province in December 2019 and keep going to effused globally. COVID-19 is reasonably hazardous and reasons serious respiratory diseases. It is seen as bronchitis, bronchiolitis or pneumonia particularly in patients with chronic ailments, immunocompromised persons and the aged. This review will sum up the present information on the biology, resources, and survival capacity of human coronaviruses. It will as well provide information on the extremely pathogenic Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and the recently defined outbreaks of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV).

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