Toxic impact of chlorpyrifos, an organophosphate pesticide, on serum biochemical parameters of Anabas testudineus



The serum biochemical effects of Anabas testudineus were examined after exposure to sublethal concentrations of chlorpyrifos (0.125, 0.250 and 0.375 mg/L) for 7, 14 and 21 days. Serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP) activities, bilirubin levels increased in response chlorpyrifos exposures at all exposure periods. On the 7th day, the sodium and potassium levels increased only at the concentration of 0.375 mg/L. On the 14th and 21st days, sodium levels increased depending on concentration, potassium levels were higher than the control. Calcium levels decreased on 14th and 21th days. Phosphorus levels decreased on 14th and 21 th days. On the 7th, 14th and 21st days, glucose levels increased and protein levels decreased. The cholesterol level was in a decreasing trend with increase in the concentrations of chlorpyrifos on 7th days. On the 14th and 21st days, cholesterol levels increased depending on concentration. This study shows that chlorpyrifos, in subletal concentrations, elicits serious metabolic disorders in A. testudineus.


Anabas testudineus; Chlorpyrifos; Serum parameters; Enzyme activities; Metabolites; Ions

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